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Insufficient efficacy is the major obstacle to the success of human parasite vaccines

doi: 10.3389/fncel.2024.1426231 Received 01 May 2024 Accepted 14 June 2024 Published 05 August 2024 Volume 18 - 2024 Edited by Wensheng Lin, University of Minnesota Twin Cities, United States Reviewed by Zhixin Lei, Wuhan University of Technology, China Carlos Matute, Achucarro Basque Center for Neuroscience, Spain Updates Copyright 2024 Stys, Tsutsui, Gafson, t Hart, Belachew and Geurts

35 Because a number of bacterial proteins are Mn dependent, host-mediated Mn sequestration has the potential to disrupt bacterial pathogenesis

Beyond FDA-approved drugs, several experimental iron chelators have demonstrated strong potential for intranasal brain targeting

Lheureux, S., Braunstein, M

F., & Giovannucci, E